Resveratrol, GABA, L-Glutamine

Medications
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So these are the supplements I’ll be trying out over the next month. They’ve just arrived.

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I read that glutamine doesn’t pass the blood brain barrier if you’re taking it for the brain.

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I don’t know about GABA, they have to cross the blood brain barrier to have effects.

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You should consider trying Resveratrol.

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Wel I’ve just taken 1000mg of L-Glutamine. :man_shrugging:

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I recently bought GABA, only taken it a few times, haven’t made up my mind about it yet, I don’t know if it is doing anything, but I haven’t had any negative reactions to it. 500mg/daily.

I’ve read reports that say GABA may cross the blood brain barrier. I’ve also heard it crosses the blood brain barrier in small amounts, and when it does it is removed much faster than it enters, so it may have negligible effects.

I read when GABA is paired with L-theanine it can help quite a bit with sleep. I also read when GABA is paired with L-arginine it greatly increases the ability of GABA to cross the blood brain barrier. GABA may also effect the enteric nervous system.

In the end there is a lot of conflicting information and reviews out there, all I can suggest is try it and see how it affects you. There really isn’t any definitive information that I could find.

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Be careful with the GABA. It is proven to have moderate interaction with many ap’s.

I considered trying it myself, but afraid of the possible interacton. If I did try it, I wouldn’t take it at the same time of day as AP’s.

Good luck and let us know how you get on :blush:

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Hmm… Maybe the L-Glutamine is chilling me out as intended. It’s too early to tell though. Could be the placebo effect.

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I definitely think that the L-Glutamine is doing something. It feels like I’ve taken a few benzos. It’s quite strong.

I did take it with my broccoli sprout extract though, so maybe it’s a double whammy.

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LS!
I recently have read that resveratrol attenuates eotaxin 1 or CCL11, a gene that is on the loose and spews aging cytokines once you have a psychiatric illness.

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Well I’ve just taken resveratrol even though I’m sure it interacts with abilify. Time will tell.

Being a guinea pig is fun.

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Came across this: Nasal lining used to breach blood/brain barrier -- ScienceDaily

Given that many sources on the Internet say that GABA cannot pass through the blood brain barrier when you swallow a capsule, would it be possible to snort some GABA up your nose and bypass the blood brain barrier so the GABA is more effective. Has anyone heard of this before?

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Doesn’t sound very safe. I don’t think it has ever been studied.

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It could be dangerous, its a human body lol

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I think this was just the placebo effect. I don’t notice anything now.

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Good luck hopefully you have positive benefits from them.

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Apparently you have to have that procedure done that is described in the article I linked to earlier to bypass the BBB. Simply snorting GABA probably wouldn’t have any effect: Can nasal drug delivery bypass the blood-brain barrier?: questioning the direct transport theory - PubMed

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How has GABA worked for you?

I started on it today. I think it helps me relax and I was able to take a nap and daydream. Haven’t been able to do that in a long time.

I guess I’ll try it for a while and see what happens.

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I didn’t even take them in the end. I figured out that coffee was my anxiety culprit and cut that down instead.

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