Patients with epilepsy are nearly eight times more likely than people without the condition to experience psychosis, show results of a systematic review and meta-analysis.
The study, conducted by David Cotter (Royal College of Surgeons in Ireland, Dublin) and colleagues, also estimated that 5.6% of all patients with epilepsy and 7.0% of those with temporal lobe epilepsy have comorbid psychosis, which is largely consistent with the findings of previous qualitative reviews.
As reported in BMC Psychiatry, the researchers analysed data from 58 studies investigating the prevalence of psychosis in patients with epilepsy. The majority (n=48) of studies were cross-sectional, nine were cohort studies and there was one case–control study.