In this guideline, ‘complex psychosis’ refers to a primary diagnosis of a psychotic illness (this includes schizophrenia, bipolar affective disorder, psychotic depression, delusional disorders and schizoaffective disorder) with severe and treatment-resistant symptoms of psychosis and functional impairment.
People with complex psychosis usually also have 1 or more of the following:
- cognitive impairments associated with their psychosis
- coexisting mental health conditions (including substance misuse)
- pre-existing neurodevelopmental disorders, such as autism spectrum disorder or attention deficit hyperactivity disorder
- physical health problems, such as diabetes, cardiovascular disease or pulmonary conditions.
https://www.nice.org.uk/guidance/ng181/chapter/Recommendations#who-should-be-offered-rehabilitation