Regular aerobic exercise is positively associated with hippocampal structure and function in young and middle-aged adults


This reminded me of a recent news report: “The hormone irisin is found to confer benefits of exercise on cognitive function

“Exercise is known to have positive effects on brain health, which is why identifying key mediators of those neuroprotective benefits, like irisin, has become such a critical goal of research,” said Wrann, who also serves as an HMS assistant professor of medicine and leader of the Program in Neuroprotection in Exercise at Mass General.

Using mouse models, the team showed that genetic deletion of irisin impairs cognitive function in exercise, aging, and Alzheimer’s disease, which was in part caused by alterations of newborn neurons in the hippocampus.

Publication: “Exercise hormone irisin is a critical regulator of cognitive function