Prucalopride Studied For Treatment of Cognitive Impairment

How are other treatments for cognitive impairment coming along?

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Unfortunately they only care about positive symptoms to the detriment of quality of life

Subduing us to the point of exhaustion is seen as treatment, and compliance as recovery

Suppose it’s better than being institutionalised

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The researchers found that, compared with those taking the placebo, the volunteers taking prucalopride were both significantly better at the memory test after the scan, and also had fMRI scans indicating enhanced activity in brain areas related to cognition. The increased activity was in areas associated with memory, such as the hippocampus (in the centre of the brain) and the right angular gyrus (towards the rear of the brain).

Prucalopride is a 5-HT4 agonist which is taken primarily for constipation. It doesn’t have significant side effects if taken under medical supervision, although doctors caution of the possibility of headache, gastro-intestinal symptoms such as abdominal pain, nausea and diarrhoea, and fatigue or dizziness; there were no significant side-effects shown by any of the volunteers taking prucalopride in this study.

It was healthy volunteers and only for 6 days but certainly should be studied more.

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Great news. But we need a proper trial with Cohen d difference calculated (e.g. < 0.5 SD is nothing)

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It can be shiped from xHIBA more eveb cheapper

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