NSI-189 Phase 2 update

https://globenewswire.com/news-release/2017/12/05/1228988/0/en/Neuralstem-Presents-Positive-Updated-Data-from-Phase-2-Study-of-NSI-189-in-Major-Depressive-Disorder-at-the-56th-American-College-of-Neuropsychopharmacology-ACNP-Annual-Meeting.html

"40 mg dose showed statistically significant improvement on Cogscreen objective cognitive measures of attention and memory

Two additional self-rated secondary endpoints (CPFQ and QIDS) showed statistically significant improvements in depressive symptoms with procognitive benefits, reinforcing the benefit with SDQ endpoint reported previously

NSI-189 appeared to be safe and well tolerated with no serious adverse events"

NSI-189 is “in clinical development for MDD and in preclinical development for Angelman syndrome, irradiation-induced cognitive impairment, Type 1 and Type 2 diabetes, and stroke.”

More info:

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Probably a load of crap

Why is that?

1515

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Going good… we need it…!!! I have serious cognitive impairment…!!! Hope it passes phase 3 as well… Sup @twinklestars… ?? What are u doing…??

Did not reach any significant end points … what the hell…!!!

They’re testing it in major depressive disorder, and it didn’t improve patient scores on the scale they use for that, MADRS. But it did show a statistically significant benefit on Cogscreen measures of attention and memory.

It’s procognitive.

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