I understand with the dopamine antagonism.
why is the anti-psychotic created to affect the serotonin, histamine, and other receptor sites?
What is the function
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I dont know, but maybe histamine to be more calming?
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I think it is just ways of addressing the chemical imbalance in your brain. Too much of certain chemicals make you ill and they try and address this. If your asking what an imbalance of a certain chemical does, I am not too sure.
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I’d like to know that myself.
I mean if the meds are hitting our dopamine and serotonin then how can they be amazed at when we have no joy and happiness
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Antipsychotics function is to balance neurotransmitters which in turn make new pathways for nerves to get connected in the brain.
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It’s all so unknown to me what is going on. It scares me a bit.
Is this true?
Can you back up your statement?
If this is true we all might have a chance at full remission in (depending on the person) a few years at least for me as a non sz
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You can’t imagine how good I feel right know knowing this, it’s like I found hope again.
My therapist and pdoc said I will quit meds in a few years depending on how the illness evolves and my body and mind will adjust. I am so happy guys.
Now I understand why I need to work out, read, learn, eat healthy, do therapy, take my meds and have a great overlook over my mental and psyzical health.
Thank you @Winterblues you are awesome, keep on grinding like a true champ.
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Yeah it’s rewiring of neurotransmitters
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Here comes @anon9798425 with the true answer haha
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It’s a hit and miss. Potential drugs can be chosen for further research based on their receptor affinities, but we don’t know for sure why some drugs work better than others, and they weren’t engineered to work well by targeting specific receptors. Seroquel is one drug that seems to work partly through its effects on serotonin. Serotonin affects dopamine transmission. But we don’t know specifically why or how it works. In the end, the effects are probably not because of regulating levels of neurotransmitters, but because of other effects on these brain networks that we’re only just beginning to understand, such as reorganizing connectivity patterns and changing genetic expressions inside brain cells.
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You mean a change in the adn of a cell?
From what you’ve said I understand that antipsychotics block old disfunctional pattern in the brain and make the brain use the functional ones more and more until it reached a point when them are the only one used in the procces of function. Did I understood right? I have zero knologe in the chemical procces of antipsychotics in the brain.
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Yes. Epigenetic changes to the DNA of the cell.
Yes, sort of. They do regulate neurotransmitter levels, but the antipsychotic effects are from other effects that may or may not be related to this. Connectivity is patterns in which cells are connected to which (structural connectivity) and patterns in how they communicate (functional connectivity). I’m no expert on how antipsychotics work, either, but I do know that they modify connectivity patterns and change genetic expressions, and that these are more likely causes of their antipsychotic effects than the neurotransmitters they affect.
So basically they work in complex ways to make the brain cells communicate in a way that is more similar to how healthy brain cells communicate. There’s a lot of interesting on-going research on this.
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I should check them out.
Sounds preety complex
I would struggle to understand most of it, even though I have completed a few relevant neuroscience courses and got A’s… It’s very complex.
I always wondered what college speciality do you do. What it is?
It’s a bit of a lot of things, but I’d rather not say what degree I’m taking.
What did you change your name to previously @anon92220549 ??
Damn. You made me all curious, mistery man
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I had more changes of names but didn’t post a lot under them.
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