I looked up why l theanine might help with reducing alchohol cravings, and it seems to have to do with GABA. I guess it makes sense since in sz the glutamate/GABA balance is disrupted. And in chronic alcohol consumption GABA is reduced, with increased glutamate which can cause anxiety.
But, apparently not everyone has the same issues with glutamate, I read of a specific SNP on one of the glutamate associated genes. They think that might be why it’s been so difficult to get a glutamate modulating med on the market even though they know glutamate is involved in sz… it works for some, but not all. And also looks like it tends to work better earlier in the illness, that the brain adapts somewhat later on.