Other than iti-007 which will be available after at least 3-4 years from now for most of us …What are the other investigational Aps ?
1 Like
I think i would immigrate to be on iti-007
Anon10
August 5, 2016, 12:24am
4
Seriously a low dose of a weight neutral med should do you some good.
Besides, Iti007 isn’t out till 2017-'18 right?
Do u have good insurance coverage? It might b kind of expensive.
You are a very negative person @eduvigis
I don’t think this post is suitable for this forum.
@Rhubot , @Moonbeam , @Minnii .
1 Like
Guys, please flag when you see it’s innapropriate. It’s easier than calling us
If I am wrong, how to deal with this situation?
1 Like
Oh no, you’re not wrong. I deleted the post. I just said to flag in the future.
There’s a little flag on the when you click on the … at the bottom of the post. Click it when you see something you seem it’s inappropriate.
1 Like
Ok, I will flag the post which is inappropriate to me even is appropriate to others.
1 Like
When you see one you think is inappropriate, flag it so we’ll make the judgement call if we think it is or not.
Oh, I know it. There should be a post about how to use that icons.
1 Like
Anon10
August 9, 2016, 1:51pm
15
I cant even remember what i posted!
But seriously u guys need to grow up…
Your post is already deleted.
What do you mean “grow up”?
Anon10
August 9, 2016, 1:57pm
17
No, what did I say that was offensive? Do u remember? Could u tell me?
Try to see positive side of the life rather then being pessimistic…
We all need to grow up mah…
just chill…!!! i like U bro…our post is a sensitive matter to other people…!!
Lets abide by the rule of the forum…!!!..common mah… Smile…!!!
You can ask moderator for your post and why it is deleted.
1 Like
Check out rapastinel. It’s a proven antidepressant possibly working as an adjunct to or replacement for antipsychotics:
L Rajagopal, JS Burgdorf, JR Moskal and HY Meltzer,
Behavioural brain research , Feb 2016 15
GLYX-13 (rapastinel), a tetrapeptide (Thr-Pro-Pro-Thr-amide), has been reported to have fast acting antidepressant properties in man based upon its N-methyl-D-aspartate receptor (NMDAR) glycine site functional partial agonism. Ketamine, a non-competitive NMDAR antagonist, also reported to have fast acting antidepressant properties, produces cognitive impairment in rodents and man, whereas rapastinel has been reported to have cognitive enhancing properties in rodents, without impairing cognition in man, albeit clinical testing has been limited. The goal of this study was to compare the cognitive impairing effects of rapastinel and ketamine in novel object recognition (NOR), a measure of declarative memory, in male C57BL/6J mice treated with phencyclidine (PCP), another NMDAR noncompetitive antagonist known to severely impair cognition, in both rodents and man. C57BL/6J mice given a single dose or subchronic ketamine (30 mg/kg.i.p.) showed acute or persistent deficits in NOR, respectively. Acute i.v. rapastinel (1.0 mg/kg), did not induce NOR deficit. Pre-treatment with rapastinel significantly prevented acute ketamine-induced NOR deficit. Rapastinel (1.0 mg/kg, but not 0.3 mg/kg, iv) significantly reversed both subchronic ketamine- and subchronic PCP-induced NOR deficits. Rapastinel also potentiated the atypical antipsychotic drug with antidepressant properties, lurasidone, to restore NOR in subchronic ketamine-treated mice. These findings indicate that rapastinel, unlike ketamine, does not induce a declarative memory deficit in mice, and can prevent or reverse the ketamine-induced NOR deficit. Further study is required to determine if these differences translate during clinical use of ketamine and rapastinel as fast acting antidepressant drugs and if rapastinel could have non-ionotropic effects as an add-on therapy with antipsychotic/antidepressant medications.
1 Like
How long for before this " Rapastinel" comes out?
Spirits are low today could use some good news on a new medication. Also Iti-007 should be out in a year and a half at the latest. That is according to the most recent article that I read. Not 3-4 years like somebody said earlier.