Is it worth it to come off meds to lose weight?

Both (though Vraylar is called Reagila here in Europe), but only up to 3 mg of the former. I’m currently taking 350 mg of clozapine, and I’m thankful to have escaped the weight gain, but sedation (so I take it close to bedtime) and disruption of the swallowing reflex (so I have to chew carefully and put a towel over my pillow) is bad enough. For me it does not do anything for negative symptoms but I’ve read that for some people it is the best; the explanation is probably that my negative symptoms are due to depression and not psychosis.



Much of my negative symptoms went away after sertraline was increased and so were related to depression.

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