Increased plasma Brain-Derived Neurotrophic Factor (BDNF) levels in females with schizophrenia

firemonkey · May 16, 2019, 10:25am

ncbi.nlm.nih.gov

Increased plasma Brain-Derived Neurotrophic Factor (BDNF) levels in females with schizophrenia.

CS Weickert, CH Lee, RK Lenroot, J Bruggemann, C Galletly, D Liu, R Balzan, A Pillai, P Buckley and TW Weickert, Schizophrenia research, May 2019 11

Brain-Derived Neurotrophic Factor (BDNF) acts as a critical regulator of synaptogenesis and synaptic plasticity. Sex differences have been demonstrated in many aspects of schizophrenia. This study tested for sex-specific differences in peripheral BDNF levels in people with schizophrenia and healthy controls. We measured circulating plasma BDNF levels in 95 people with schizophrenia and 80 healthy controls. Plasma BDNF levels were significantly elevated in females with schizophrenia compared to males with schizophrenia and to female healthy controls. These results suggest that sex differences in peripheral BDNF levels may contribute to other sex related differences in schizophrenia.

twinklestars · May 16, 2019, 4:13pm

I wonder if this means MIN 101 (Roluperidone) will work better for males.