Herpes encephalitis

a case of herpes can make a person psychotic too

Psychosis and herpes simplex encephalitis. M Schlitt, F D Lakeman, R J Whitley Southern Medical Journal (Impact Factor: 0.92). 12/1985; 78(11):1347-50. Source: PubMed ABSTRACT
We have reported an unusual presentation of herpes simplex encephalitis
in a patient with a 3 1/2-year history of a schizo-affective disorder.
In the month immediately before diagnosis, the patient lost contact with
reality and became violent. After successful treatment with
antipsychotic medication, he had agitation and disorientation, as well
as fever and cerebrospinal fluid pleocytosis. There were no focal
neurologic findings. When a low-density lesion in the right temporal
lobe was defined by computerized axial tomography, brain biopsy and
culture isolated herpes simplex virus type 1. After therapy with
vidarabine, the patient regained independence in simple daily
activities. This case stresses the possibility of herpes simplex
encephalitis in patients with an acute mental change.

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