It did for me! I am so unlucky because it fixed my negative symptoms! The FDA has warnings about those:
“The U.S. Food and Drug Administration (FDA) is warning that compulsive or uncontrollable urges to gamble, binge eat, shop, and have sex have been reported with the use of the antipsychotic drug aripiprazole (Abilify, Abilify Maintena, Aristada, and generics).”
I wasn’t fully stable on 120mg Latuda and gave me terrible akathisia and nausea/vomiting. I read that its 55% weaker than Risperdal. Now I am stable on just 4mg Risperdal!
Abilify, Rexulti and Vraylar are the only partial dopamine agonists. Rexulti has the same FDA warnings as Abilify so I refused it when my pdr prescribed it. I didn’t pickup the prescription. Vraylar is supposed to come out here in Canada by end of this year hopefully.
I went onto Abilify and suffered a relapse. It really, really didn’t agree with me. My sleep was disrupted to such an extent than I became paranoid and hostile.
Your dopamine works on synapsis with 2 ends, one sends out the dopamine signal, the other receives the dopamine signal. Presynaptic means the end which sends out the dopamine signal while post synaptic is the end that receives it. Lumateperone works as a presynaptic agonist and a post synaptic antagonist