Family History of Mental Disorders Linked to Higher Risk for Autism Spectrum Disorder

History of mental and neurological disorders in first-to-fourth degree family members is associated with an increased risk for autism spectrum disorder (ASD), according to study results published in JAMA Network Open .

The study cohort included 567,436 index persons, 51.3% of whom were male. The mean age of all participants at the end of follow-up was 14.3 years. The prevalence of ASD with intellectual disability (ASD-ID; n=2566) and without ID (ASD-No ID; n=8354) was 0.4% and 1.5%, respectively.

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