Experiencing a new side effect

I’m not sure if its due to my increase in lamotrigine (lamictal) or me just starting Wellbutrin (it’s only my first day on it)

I am crazy itchy!!! So much so I can’t sleep because of it. My skin is all scratched up but I can’t seem to help it, I can’t get any sort of relief unless I itch.

My body (also blood) feels really hot too. It’s kinda like when you take Niacin for the first time and you get that weird hot flush feeling. If anyone knows what I mean.

I’m itchy everywhere! No signs of rash though. What should I do? It’s driving me crazy!

Wellbutrin can increase your body temperature. But the itchiness is a bit concerning. Maybe ask your boyfriend to call the pharmacy to see if it’s possibly a side effect?

Also try using ice on itchy areas it can soothe it. Also aloe may help?

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Lamotrogine can create serious rashes aparantly it’s a common side effect.

Speak to your psydoc.


Honey I would stop the Wellbutrin until you can get a hold of your pdoc, than can be a sign of an allergic reaction. I’m not trying to scare you, but just to be safe. Take care.

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I don’t think stop any meds but rather get hold of your psydoc today and let them know

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Maybe a nice hot shower would help ?

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also take some benadryl if you have some


Yeah, I’ve decided that later on today (it’s 4:21AM and I still haven’t been able to sleep) I will call the nurse line.

I’m not super worried as I don’t have any sort of rash or hives and I have experienced itchiness as a side effect to medication in the past.

I will make sure to check with a professional though, hopefully I won’t have to stop Wellbutrin as I was feeling quite hopeful that it would help my motivation.

I did more today then in the past month but it’s only day one of Wellbutrin so it’s most likely just in my head. Either case it’s nice, minus the itching.

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Just thought of this, you posted pics of a lot of clothes you were washing and handling, clothes that have been sitting for log periods of time can make you itch. I have found this with shirts that hang in my closet for a year or so.


I get itches on my feet mostly. Unbearable, so I scratch them until they bleed. I would rather have the sting of bleeding than the itch. it seems to be the only way I can get the itching to stop, thus occassionally I have scabs on my feet and lower legs. I don’t know any way else to stop it Scratch it unitl it bleeds is what i do, can’t say i advise you to do the same.

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As posted on the say anything thread:

Sooo I feel a little silly. It’s around day three since I first started noticing a side effect of itchiness, increased body heat, a slight rash here and there on my body, and general discomfort.

This started happening after I increased my dose of lamotrigine and started Wellbutrin. My doctor told me if I got any sort of rash it was very serious and I should stop the meds and go see him immediately.

But I’m just having so much anxiety. I don’t want to wait in the doctors office with all those people. I haven’t even call the nurse line because I can’t make phone calls.

I asked my boyfriend to call but he said they would just tell me to go to the ER so what’s the point.

I’m worried though if it’s serious. If I get scars it would literally ruin my life. All I have going for me is my beauty. I would kill myself if anything happened that would ruin that.

I’m also worried that they’ll make me discontinue my lamotrigine and Wellbutrin. It’s taken me SO long to get to a proper dose, and I was excited to try Wellbutrin.

I’ve never been good at taking pills, but this time I was awesome. Didn’t miss any days. Started at a micro dose and slowly increased it a little every week.

I’m so sick of taking pill after pill. I’ve tried literally over 20 without success. I’m really losing hope. If I have to go back to being unmedicated I don’t know how long I’d last.

I’m not sure what to do. Maybe wait and see if it gets worse? But I do have a rash around my armpits which is something that happens with reactions to lamotrigine.

I looked up pictures of a lamotrigine rash (yucky) and the ones that aren’t bad look like mine does.

What if I’m just being a hypochondriac. Maybe it’s in my head. I was a little worried about getting a rash from it so maybe I just convinced myself that it’s a big deal? Like a placebo thing.

What should I do? Keep in mind I can’t make any phone calls. I also really hate leaving my house unless it’s a life or death situation.

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Get to the Doctor right away, have your boyfriend call


It could very well be a life or death situation. Go to your doctor immediately! Have your boyfriend call. If you’re having an allergic reaction, you could stop breathing. I’m not trying to scare you. I’m just trying to make sure you know how serious this is.

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Yes you guys are right. I’ve just been putting it off because I’m scared, but that’s not a good excuse.

I will get him to call when he wakes up. As for me, it’s 5AM so chances are I won’t sleep at all which makes me feel better about stopping breathing, feel like it’s more of a risk if I’m sleeping.

It’s been three days of me not being able to sleep until 5-6AM. Maybe this is also a side effect.


If you experience any of these symptoms, skip the doctor and head straight to the ER

joint pain
muscle pain
general discomfort
swelling of the lymph nodes around the neck
high count of eosinophils (a type of immune cell) in the blood

In very rare cases, you may develop Stevens-Johnson syndrome or toxic epidermal necrolysis while taking Lamictal. The symptoms of these conditions are:

multiple organ failure

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