Does Anyone Know How I Can Find Out

You might want to look into whether any studies are being conducted near you on this subject. Volunteering for the study could benefit researchers.

3 Likes

I think I at least found the protein encoding gene number: 5045

1 Like

Might be a good idea. Thanks.

2 Likes

Aha! I finally found something! This does not tell me, specifically, how common the rs4702 gene mutation is in schizophrenics, but it does tell me that it seems to be present in about 30 - 50% of the general population!

Woohoo!

rs4702
Current Build 154

Released April 21, 2020

FEEDBACK
Organism
Homo sapiens
Position
chr15:90883330 (GRCh38.p12) Help
Alleles
G>A / G>C
Variation Type
SNV Single Nucleotide Variation
Frequency
G=0.341082 (42829/125568, TOPMED)
G=0.438634 (49520/112896, ALFA Project)
G=0.35591 (11157/31348, GnomAD) (- 16 less)
G=0.3538 (1772/5008, 1000G)
G=0.4004 (1794/4480, Estonian)
G=0.4385 (1690/3854, ALSPAC)
G=0.4539 (1683/3708, TWINSUK)
G=0.4549 (1333/2930, KOREAN)
G=0.4208 (877/2084, HGDP_Stanford)
G=0.3081 (583/1892, HapMap)
G=0.4525 (829/1832, Korea1K)
G=0.416 (415/998, GoNL)
G=0.393 (236/600, NorthernSweden)
G=0.455 (243/534, MGP)
G=0.244 (108/442, SGDP_PRJ)
G=0.463 (100/216, Qatari)
G=0.491 (104/212, Vietnamese)
G=0.27 (13/48, Siberian)
A=0.47 (19/40, GENOME_DK)

Took me long enough.

1 Like

I think I’m getting closer:

That article has a chart that seems to compare rs4702 genes in “SCZ” and “Control.” I think that I need a higher resolution version of it to read it clearly. Maybe I can buy a copy.

1 Like

Why do you want to know about this gene? Curiosity? I read somewhere that we just know 20-25% of sz genes so far and that its too complicated.

1 Like

Because some research indicates that having a mutation in just one nucleotide, at rs4702, means that the coronavirus might multiply at one third the rate in the brain than it would normally multiply.

The reading I’ve done so far may indicate that this mutation is very common in people with psychotic disorders. Indeed, it seems to be common in the general population.

I think that I would feel much safer working a job in which I had some human contact if I could confirm that I was among a bunch of mutants who would probably only get mild covid if we ever got it.

2 Likes

Maybe that’s why my covid symptoms just lasted 2-3 days but they were extreme too but didn’t require hospital. I am just 30 y.o. btw so its much worse for older ppl. Anyways I wouldn’t risk getting covid even if I knew that I have a protecting gene. Genes aren’t the only factor, it largely depends on your age and immune system. I also read that it depends on your vaccines history, some older vaccines protected from severe symptoms, it was milder.

1 Like

If anyone is curious, here are pie charts for a few different populations, but not schizophrenics:

Apparently, DNA tests are available for it. I might get one.

I decided to order a 23andme.com test kit. I called customer service. They said that even on their most inexpensive tests, they provide the data on rs4702 on chromosome 15 in the raw data, although they do not provide an interpretation of that data, and state that it cannot be used for medical purposes.

I’m excited. Maybe in 2 to 4 weeks, I’ll find out that I’m a covid-resistant mutant! :muscle:

I mailed my saliva sample today. Maybe I’ll have may answer within 2-3 weeks.

Just be careful, having covid19 isn’t fun.

1 Like

I’m still waiting for the sample to get to them, apparently.

They finally received my DNA today. Now they say they are extracting it.

I got my results:

So, it turns out that although I had a psychotic episode, I do not seem to have the G / G rs4702 gene mutation. It seems that I did not find out that I’m a Covid resistant mutant by virtue of rs4702.

Maybe I can still avoid covid the old fashioned way for a while: By trying to stay away from people.

More posting in my own little thread:

I got some more information on the study that was conducted on rs4702 and covid-19:

As you can see in the pictures of the cells, it seems that they may have only tested the AA type and the GG type, not the AG type, which my test says I am.

That leads me to wonder: What if the G gene is ‘dominant’ and the A gene is ‘recessive?’ I’m trying to find out if that may be the case now.

@freakonaleash, I understand that you are an adjunct professor of biology, at times. Do you happen to know of any resources where I might look up whether a gene is known to have one dominant and one recessive nucleotide?

Thanks in advance for useful information on this.

No, sorry, I don’t know of any such resource.

1 Like

Thanks for the answer. That may save me a good bit of time looking for such a resource.

Disclaimer: I’m not making any medical recommendations.

You know what? The scientific evidence is just in its beginning stages; but, the more I consider some available information, the more I’m beginning to think that both the GG and the AG genetic combinations for rs4702 seem to offer some resistance to coronavirus.

I think that I’m going to think about it for a day or more, and then possibly bet my health and my life on the supposition that my A/G rs4702 genetic makeup affords me some resistance to a severe novel coronavirus infection.

This topic was automatically closed 14 days after the last reply. New replies are no longer allowed.