Schizophr Res 2013; Advance online publication
medwireNews: UK research indicates that children with asthma and eczema are significantly more likely to have psychotic experiences during adolescence, boosting a previously reported relationship between schizophrenia and atopic disorders.
Golam Khandaker (University of Cambridge) and colleagues studied data on 7814 children who were followed up from birth to the age of 10 years. During this time, 14.4% were physician-diagnosed with asthma, 12.7% with eczema, and 7.3% with both asthma and eczema.
Among 6784 of the children who were interviewed at age 13 years, 14.2%, 15.2%, and 16.0% of those with eczema, asthma, and both conditions, respectively, had had psychotic experiences in the previous 6 months compared with 11.7% among those with no atopy.
This equated to a respective 33%, 37%, and 44% increased odds for psychotic experiences compared with those with no childhood atopy, after adjustment for confounders such as gender, socioeconomic status, and ethnicity.