So I started taking antidepressants a little over a year ago and they worked great for about 6 months… then slowly I lost my motivation and energy again… I stopped taking them all together a few weeks ago
Is it possible for antidepressants to stop working?
YES!.. i was on the strongest AD, an MAO-Inhibitor, and it lost its effectiveness.
It is called “Tachyphylaxis” (google it + depression)
I stopped taking my MAO-Inhibitor for a month or two, then started taking it again, and now it is working again, but not as good as the first time I took it.
The strategy to treat Tachyphylaxis is either to increase dose, switch medicine, or stop it for a period of time and then start again.