Anyone respond well to Haldol but had to replace it?

I was on Risperdal for over 10 years and overtime it became ineffective. 3 mos ago i was prescribed 100mg daily of Haldol which has worked well but i just found out that is the maximum dose and it can lead to heart problems. Anyone find a good replacement for Haldol that has worked well for them that can be recommended?

my Haldol hasn’t been replaced yet, but I figure my new pdoc that I see in march might replace it I don’t know with what yet but this thread is a good idea

Latuda is a good drug if you can afford it

P-docs aren’t exploring this yet, but Charlotte’s Web Hemp Oil (CW) is the commercially available version of the cannabidiol (CBD) in the following clinical studies.

My son uses it and while it’s NOT a replacement for his prescribed medicine, it really helps smooth out his moods. With more testing and standardized dosages, use in the sz and bipolar community will expand. NEVER REDUCE PRESCRIBED MEDICINES WITHOUT DOCTOR SUPERVISION when adding in CW to your routine. NOTE: no side effects to using CBDs!!

For bipolar, the antipsychotic effects of CBD act in a similar way to a common antipsychotic, haloperidol (haldol). Antipsychotic effects of high-dose oral CBD showed 60–69% improvement in scores on the Brief Psychiatric Rating Scale. (This is a long read by the Journal of Pharmacology. Check your calendar.)

Time Magazine article gives the best description ever about using CBDs for treating the psychosis of schizophrenia!!

Investigators found that THC and CBD had opposite effects on the brain. CBD is capable of reducing psychotic symptoms and did not produce a “high” feeling. CBD is capable of reducing anxiety from THC. (Save a few nights of your spare time to read this one.)

CBD was shown to reduce anxiety in patients with social anxiety disorder.

CBD has antipsychotic effects as observed using animal models and in healthy volunteers, appearing to have pharmacological profile similar to that of atypical antipsychotic drugs. Additionally, CBD was effective in open case reports and clinical trials in patients with schizophrenia with a remarkable safety profile. (Sorry, I wasn’t aware that the link would post half of the entire study on this page!! :flushed: )

20+ more clinical studies on cannabidiol (lots of PubMed) here:

Information about Charlotte’s Web (+ getting a cheaper price) – this IS NOT A SALES SITE, it just gives easy step-by-step so you get the not-so-easy to find discounted price.

It’s legally allowed to be shipped in the U.S. as a dietary supplement, no cannabis doctor recommendation needed.
Charlotte’s Web Medical Hemp Act of 2014 (H.R.5226)
Amends the Controlled Substances Act to exclude therapeutic hemp and cannabidiol from the definition of “marihuana…” (yes THEY spelled it differently!)


Thanks @Jimgym and everyone else for your response

I’m astonished that you can take 100 mg daily of Haldol. Forty milligrams a day was pure hell for me. I was on the time released shot for a long time. That was tolerable, but it wasn’t good.


Crimby you got me thinking so i checked the bottle and i’m on 5mg twice daily way below the 50mg twice daily i thought. I apologize for the misinformation although i have been having some regular chest pains since starting Haldol. Thanks for bringing it to my attention that 100 mg would be a highly unusual dose.

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I took Haldol, but had wicked dystonia.

Perphenazine works for me . . .


I took it for a year, then it stopped working. I take thorazine now

Lol…yeah…I too was like :thinking::fearful:
I’m pretty sure 100mg would be lethal.