Chandley, M. J., M. N. Miller, et al. (2009). “Increased antibodies for the alpha7 subunit of the nicotinic receptor in schizophrenia.” Schizophr Res109(1-3): 98-101
Many association studies show that acetylcholinereceptors such as nicotinicreceptors or muscarinic receptors are related to schizophrenia.(Freedman, Leonard et al. 2001)
Alpha 7 CNS nicotinic acetylcholine receptor is a widely accepted gene linking to schizophrenia. In postmortem studies, the acetylcholine receptor numbers are severely decreased in schizophrenia patients.(Gault, Hopkins et al. 2003)
so, if you’re immune system heats up, like if you’re sick, you are emotionally upset, you are hot, you exercise too much, your immune system triggers your psychosis.
that is something the researchers are still looking at. here are all the research papers cited by the individual who wrote the research paper to support his statement that Sz is autoimmune . it doesn’t paste well, so here again, is the link to the paper, and there’s quite a bit about it on the NIH or PubMed website as well
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Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia treatment by drugs changing serotonin and dopamine concentration. Despite of such treatment, majority of schizophrenia patients still have very poor prognosis. Thus, the neurotransmitter imbalance theory is not correct.
Pretty big jump to say that because schizophrenia is difficult disease to treat that the established theories are wrong.
How effective is his treatment of schizophrenia? If it worked better than the established treatments then he might be on to something. If it doesn’t then he’s full of it.
I don’t recall the writer’s exact title, but I believe he’s a Dr, from John Hopkins, moved back to his native country Taiwan. the writer is a doctor, not a patient.
the citations on the last 2 page of the paper, are other doctors and researchers, finding antibodies against acetycholine.
I’m learning there’s many antibodies against acetycholine, I’ve been tested for the 3 that have tests available on the market, and they are used predominately for MG, (eye drooping, muscle weakness caused by lack of acetycholine) Even if you have MG, this test comes back negative 10% of the time. Testing for acetycholine antibodies for MG is only available at this lab Arup, and at Mayo, I have been tested by both labs, all negative.
if you read the Sz research paper, they are looking at other antibodies against acetycholine that researches have found, but a test like this has not yet been developed, which is what a pdoc will tell you, there isn’t a test for Sz yet
