What does this receptor do? Geodon is a partial agonist and Abilify is an antagonist at that receptor so they’re opposite. I wonder what does that mean. I think my last pdoc was pissed off at me because I ask too many questions.
My risperidone is antagonist at that receptor too.
I doubt anyone here is that advanced in their knowledge. All you are likely going to get is internet searches. Here is the best I could find quickly:
"Due to the range of neurotransmitters controlled by 5-HT1B, it is associated with a range of neurological functions, including mood, memory, aggression, stress sensibility, and anxiety1. The receptor is also present in the “extended amygdala” of the brain1, a reward circuit associated with drug reinforcement. It is, therefore, unsurprising that variations in the 5-HT1B gene have been associated with addiction and obsessive-compulsive disorder in humans3. "
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Thanks, I read wikipedia but it wasn’t as precise as your article. I bookmarked your article. @Bowens
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I find it complicated and interesting that serotonin receptors can increase or lower dopamine in specific brain regions. I thought at first that neurotransmitters and receptors are independant.
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Yeah, It’s a confusing topic. It’s quite complicated.
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