I'm on 2.5mg and I tolerate it more than a higher dosage. I guess the higher the dose, the more you should worry about TD. I had muscle-twitches on higher dosages but no TD (I've used Zyprexa for about 9 years in higher dosages). When it does occur though, quit immediately. I had muscle twitches in my tongue when added with Amitriptyline, I quit immediately and it went away. If I have to chose between TD and a less working AP, personally, I would go for a less working AP, no ■■■■■■■ permanent twiching for me!