Sarcosine Reduces Symptoms in Schizophrenia

Yes - I think they ship everywhere.

I think they are a small company that is focused on things that have good science behind them in terms of really helping people with brain disorders, and who want to improve things for people. Its run by a scientist. I think they plan to come out with more products in the future.

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If you try Sarcosine - please be sure not to go over the 4 grams per day level that has been used in the research studies. Researchers have noted that high levels of Sarcosine (or Glycine, or D-serine) can actually damage your brain cells - which would obviously be counter productive.

Here is some info on this. Also - don’t mix Sarcosine, Glycine and D-serine - because you could get too much of the compounds targeting those brain receptors. Click on my post below to read the full information on this issue.

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Is sarcosine and citicoline(CDP-Choline) the same thing ?

The wiki page says:

Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. Sarcosine is formed from dietary intake of choline and from the metabolism of methionine, and is rapidly degraded to glycine 1

https://en.wikipedia.org/wiki/Sarcosine

I took citicoline for a while IIt seemed to help a bit with motivation

Well - the short answer is no - they definitely are not the same thing.

In all the clinical research studies that I’ve seen - they use Sarcosine (they have also tested Glycine too - but you have to take like 30 to 60 grams a day - which is a lot, and it causes upset stomach - so thats why most people don’t go that route).

I’m not a biologist or chemist - so I’m not sure why taking large amounts of choline and having your body convert it to sarcosine. I can only guess that the process isn’t very efficient (i.e. doesn’t work at the level that you’d need it to for it to offer a therapeutic benefit).

Thats my best guess.

I mean is citicoline(CDP-choline) as effective as sarcosine for negative symptoms ?

No - there are no clinical tests that I’m aware of that suggests that CDP-choline, or any type of choline, helps with negative symptoms.

Hi i started taking sarcosine 2g per day and N-Acetyl L Cysteine 2g per day ,how long till i feel something?

I think you want to slowly increase your dose on the Sarcosine over the next week or two , until you notice something or until you reach 4 grams a day. Most people here seem to start noticing a difference in the first week or two.

So i leave in Poland and i wanted to order Sarcosine + NAC from Profrontal.com but they are out of stock.Does Anyone know some good place to order both of this?

Most places don’t carry both of these. But you can probably buy NAC in Poland as its widely available I believe. Here are the sources I’m familiar with:

Sarcosine:

NAC:

http://www.iherb.com/Now-Foods-NAC-600-mg-250-Veggie-Caps/694#p=1&oos=1&disc=0&lc=en-US&w=NAC&rc=134&sr=null&ic=5

Thanks,i ordered sarcosine from http://www.brainvitaminz.com , let’s see how long i will wait on it.
Do you use it and does it work on you?

Do you recommend sarcosine for sza patients with a tendency toward mood symptoms? I am on three different atypical antipsychotics, Celexa, and an anti seizure medication for mood stabilization. I have pretty pronounced negative symptoms in the form of anhedonia, low motivation, poor self care habits and social withdrawal. My mood is euthymic right now and has been for years. I am just afraid that if I start taking this sarcosine, it has antidepressant properties, and it will throw me over the edge into mania or just irritability, which I despise. What do you advise? The last time I took one of your new drug recommendations to my pdoc, he said he had never heard of it and gave me the go ahead to disastrous results.

My ,sarcosine just arrived after only week of waiting.I will buy NAC and i will start test those thing together we will se how its work.Even if it won’t working next thing i will order will be Profrontal Sarcosine+NAC.

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Sqnik8,

Let us know how it goes.

Sarcosine research suggests that its helpful with the negative mood and activity symptoms that are common with schizophrenia.

We recommend you print out the research on this page:

and take it to your doctor and discuss it with him/her - and see if they think its appropriate for you.

Nobody here is a doctor so we can’t recommend it - we just point you to research that seems to indicate something is helpful, and you need to work with your doctor to decide if its appropriate for you.

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So i have been on sarcosine for 2 days now and all I can say it’s does work.I feel like i
express myself easier and I can read peaople emotion again.Words coming to my mind faster and I talk a lot more.I feel better after i wake up,more ready to go and now.I still got those racing thoughts tho about everything.

I can’t wait to test profrontal and if it will help more.
I am only on 2g/day brainvitaminz sarcosine.

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Okay, I’ve decided to jump on the sarcosine wagon. Negative symptoms are causing problems. I’ll post with my testimonial after I’ve tried it. Cheers!

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Did anyone experience less tiredness and more clarity, heightened senses and this kind of thing, or was it purely a subjective feeling of better mood?

I’ve turned into a believer in Sarcosine after a couple of months on it. I’m about 30% better at remembering to shower and such on my own when taking it daily. Seem to mentally stack tasks better. Didn’t think I was more positive while on it, but now that I’m off (my order is a week late - my fault), I’m noticing the lethargy and negative emotion.

I don’t think I’ll ever be back to 100% organized. Suspect Sz involves some sort of minor brain damage. There are parts of me that are gone for good. Just trying to be thankful that I’ve not been hit as hard as others. “There but for the Grace of God…” (sigh).

Anyhow, as someone who has tried all kinds of the other supplements out there, I can tell you that none have worked as well or as fast as this one for the Sz, and without any sort of horrible crippling side-effects that are so common with the head meds. The price is even reasonable.

Pixel.

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