Sqnik8,
Let us know how it goes.
Sqnik8,
Let us know how it goes.
Sarcosine research suggests that its helpful with the negative mood and activity symptoms that are common with schizophrenia.
We recommend you print out the research on this page:
and take it to your doctor and discuss it with him/her - and see if they think its appropriate for you.
Nobody here is a doctor so we canāt recommend it - we just point you to research that seems to indicate something is helpful, and you need to work with your doctor to decide if its appropriate for you.
So i have been on sarcosine for 2 days now and all I can say itās does work.I feel like i
express myself easier and I can read peaople emotion again.Words coming to my mind faster and I talk a lot more.I feel better after i wake up,more ready to go and now.I still got those racing thoughts tho about everything.
I canāt wait to test profrontal and if it will help more.
I am only on 2g/day brainvitaminz sarcosine.
Okay, Iāve decided to jump on the sarcosine wagon. Negative symptoms are causing problems. Iāll post with my testimonial after Iāve tried it. Cheers!
Did anyone experience less tiredness and more clarity, heightened senses and this kind of thing, or was it purely a subjective feeling of better mood?
Iāve turned into a believer in Sarcosine after a couple of months on it. Iām about 30% better at remembering to shower and such on my own when taking it daily. Seem to mentally stack tasks better. Didnāt think I was more positive while on it, but now that Iām off (my order is a week late - my fault), Iām noticing the lethargy and negative emotion.
I donāt think Iāll ever be back to 100% organized. Suspect Sz involves some sort of minor brain damage. There are parts of me that are gone for good. Just trying to be thankful that Iāve not been hit as hard as others. āThere but for the Grace of Godā¦ā (sigh).
Anyhow, as someone who has tried all kinds of the other supplements out there, I can tell you that none have worked as well or as fast as this one for the Sz, and without any sort of horrible crippling side-effects that are so common with the head meds. The price is even reasonable.
Pixel.
is there any known issue of taking profrontal with both an antipsychotic and an antidepressant?
I donāt think there is much in the ways of studies on use of Sarcosine with an antidepressant. There are studies showing that it has an antidepressant effect, which would suggest that you wouldnāt need as much of the anti-depressant. I recommend you discuss it with your doctor and point him to the research studies on sarcosine and schizophrenia:
and another study:
I am going to try this. I didnāt like how sick my meds were making me so I quit them, but the negative stuff is getting pretty bad. i hope this helps.
Today I just took my first 1g of Sarcosine from brainvitaminz.com and think it worked well on controlling my negative symptoms. Usually I would gladly stay in my own room but today I was surprised when I voluntarily chose to take my parents out to swimming at night and hang out the entire time with them without getting bored. I think I saw some improvements in alertness, attention to detail, more appreciation for how nice the night was (instead of just not caring), and maybe some ability to converse. Not sure if cognitive abilities such as attention span, response to environmental stimuli might be affected. Also not sure if I was just having a decent night due to mood swings. Might try adjusting my dosage but at the moment I donāt think I need more than 1g (Iām kind of short).
Hello, Tukey. Honestly, i donāt think 1mg taken once would have such a strong effect. I donāt know, though.
I started taking sarcosine this week and iām on my third day. Iāve been taking two 1mg doses every day and i honestly havenāt felt much yet. Iāll definitely stick to it, though. I know the effects are moderate, but i believe that iāll definitely notice any improvements. Iāll report any effects. Please keep us informed on how you`re doing with sarcosine. Good luck.
Hi, Iāve read, that Sarcosine has a half life of only 1.5 hours. Thatās very short. How come it works?
I havenāt read that anywhere - can you share with us the source of that information? (for example a link to that information).
As to āwhy it worksā - I recommend you read the research on this page:
Pharmacokinetics
For all doses, sarcosine exhibited linear kinetics, with a
Tmax and tĀ½ of ~1Ā½- 2Ā½hr and ~1hr, respectively
Safety, Tolerability and Pharmacokinetics of
Open Label Sarcosine Added on to Anti-Psychotic
Treatment in Schizophrenia ā Preliminary Study
THanks for pointing us to that paper - very interesting!
I found this hopeful:
āmost clinical studies as well as one meta-analysis, have shown significant effects of these compounds,
particularly on negative symptoms.ā
I think the short half-life is why some groups recommend a dose in the morning and afternoon.
I am not a scientist, what does that mean in day to day words
This seems like big news to me. If you use Sarcosine for 6 months it seems to reverse the damage to the glutamate system of the brain that is key in memory and cognition.
Here is what it says in regular english:
This is the first study showing that the addition to antipsychotic treatment with sarcosine for 6 months, may reverse the harmful increase in glutamate in the hippocampus that results in memory and cognition problems in schizophrenia
Background: The Glutamate system, the main stimulating system of the brain, plays an important role in the development of schizophrenia. Additionally, the Hippocampus, a structure crucial for memory and cognitive functions and rich in glutamate-oriented neurons. Sarcosine use for 6 months seems to reverse the damage done to the glutamate system during schizophrenia.
more information on the Glutamate hypothesis of schizophrenia:
There is a new poll for Sarcosine users by one of our members @everhopeful - to better get a better idea of peopleās experiences with sarcosine.
Please join in the poll and add your own experiences so we can all get a better idea of how / if this stuff is working for you.
I am in the UK and believe the current exchange rate makes it very good value. Plus, as mentioned it is always better to purchase vitamins from a safe, reliable sourceā¦