I am/was (mostly retired due to illness) a biochemist and my hubby decided some years ago to begin the tapering off the anti-psychotics after his PDoc at the time discovered that he was on too high of doses to the point it was making him a functional zombie. His words, not mine. After 20 years of the drugs, he had enough so we decided to go the natural route as he has been stable since his 20's. After some trial and error with one nasty episode post-medication this so far is what is working for him.
Everything he takes I introduce according to protocols with his PDoc knowing full well what is going on. One supplement at a time so everything is fine tuned. This, so far, has taken a year and half. It's marathon not a short race.
Vitamin B-3 (Flush) 3,000 mgs a day--He was feeling better before his episode and dropped the dose down to 500 mgs which is believed to have been a trigger for the psychotic episode.
Fish Oil-Krill-3,000 mgs a day with meals. i purchase organic/bio oils to be sure there is no heavy metals.
Vitamin C-1,500 mgs a day with meals. This was dropped from approx 3,000 mgs after Vitamin C cause gastric distress.
Folic Acid-400 mcg- With breakfast or morning snack.
Vitamin D--5,000 mgs--Will be dropped to 2,000 mgs in the spring and summer months as per RX.
Vitamin B-6-- 50 mg--With meals, 3x daily. This for depression related to his schizophrenia. The improvement with his depression on this alone has been dramatic.
Alpha Lipoic Acid--250 mg -- Currently, once a day,but does increase as needed to 3x daily. This supports glutathione production in the brain and a free radical scavenger, Basically, it cleans the nasties.
Selenium--50 ug--At breakfast. Many uses,but, includes support of inflammation, free radicals, antioxidannts.
N-Acetyl-L-Cysteine(NAC)- 600 mg--2x daily with meals.Again, as with the B3 the affects have been dramatic. His negative/positive symptoms have improved. However, this was only added within the last two weeks so we are waiting a bit longer to get excited.
Sarcosine--He was on 3 grams daily, however, it was causing extreme issues with mood, panic attacks, scared feelings and loss of sleep even when on benzos. Reduced to 2 grams daily and he slept like a kitten. Anything higher currently he will destablise. His memory, and other cogitive functions have slowly improved to the point he has been able to read books for at least 30 minutes in a go. This is something he has not be able to do in years. His attention has evened out for the moment. Still is having issues with being distracted,but, not as much as before.
We will be adding in L-Theanine, Lysine in the coming weeks. We will begin next with L-Theanine with the usual 8 weeks before anything else is added in. Again, the reason we do it this way is to make sure he is not having any adverse effects, psychotic features and to check his blood work as we go.
As to his anti-psychotics medications-- He keeps one on hand in case he destablises which is Latuda at 37mg at night. He had Olanazapine (Zyprexa) however the weight gain, the flat effect and the blood sugar issues...his GP advised to discont. the med.
Finally, I keep a careful log of everything that he takes along with all noted reactions, symptoms etc. and present that monthly to his PDoc for review.
During the course of my research, I discovered that gluten (wheat etc) may have a link to the negative/positive symptoms of schizophrenia. I am still deep in research with this avenue. If the science holds to my liking and his testing bears out what I suspect, that will be the final course of action, diet wise. There is some information out there if you are handy with the science terms or PM me.
I adore, cherish and love my spouse. I want him to have is life back as best we able to get it back. He is a musician and through it all he has been able to play. I realise this may sound like he is science fair project,but, he isn't. I would give anything for him to have one day of silence from everything. Life around here can be hard, but, he is worth it.
I hope this helps someone.