from what im hearing it should take sometime for my neurotransmitters to return to normal and i guess that can be 3-6 months... this is the response i got from a doctor on just awnsers.com
Dr. Z Mental Health Professional
Yes the Invega is definitely an extreme measure to take for just a depressive disorder especially when there are other medications to exhaust for treatment. Well the effects of Invega are not permanent now that you have stopped the medication, so those "depersonalization" and sexual adverse effects should start to lessen significantly in 3-6 months time. But if you wanted to try to boost your libido and possibly lessen your feelings of depersonalization, the use of Wellbutrin would be recommended since this medication actually increases your Dopamine and Norepinephrine levels and will help to increase your libido and can reverse any adverse sexual effects that are due to another psychotropic medication. The depersonalization/emotional numbing symptoms will also respond well to the Wellbutrin too, so this is why Wellbutrin should be a primary medication for you to reconsider, since you have taken it before.
Overall these adverse effects are not going to be permanent fixtures, so that should provide you with some relief, but because you were taking injections of the medication the adverse effects can be more long-standing and it may take a while for your neurotransmitters to return to their natural pre-morbid levels, which is why I state 3-6 months for possible resolution of these adverse effects. Still if you want to try to achieve a faster response than the use of Wellbutrin should be considered as the emotional numbing and sexual side effects are most likely due to a decrease in Dopamine and the Wellbutrin should dramatically help with this. If the depersonalization/emotional numbing symptoms are due to a Serotonin imbalance than a SSRI antidepressant can be combined with Wellbutrin, unless you have a history of seizures, drink alcohol, or a history of an eating disorder where the Wellbutrin-SSRI combination would not be recommended.