Do anti-inflammatory treatments reduce symptoms of Schizophrenia?

  • According to one trial, researchers found 3 anti-inflammatorys that helped reduce symptoms, including asprin and N-acetylcysteine (NAC). NAC is cheap and seems safer than asprin, What do you guys think?
    Here is the research trial page: http://www.ncbi.nlm.nih.gov/pubmed/24106335
  • “CONCLUSION: The results of aspirin addition to antipsychotic treatment seem promising, as does the addition of NAC and estrogens. These 3 agents are all very broadly active substances, and it has to be investigated if the beneficial effects on symptom severity are indeed mediated by their anti-inflammatory aspects.”
  • Learn about NAC treatment here: https://en.wikipedia.org/wiki/Acetylcysteine#Psychiatry
  • Also: Pregnenolone works to reduce negative symptoms too if you did not figure that out from reading the sticky post and by experimenting yourself. I have been taking Preg for 3 months and it is very helpful for negative symptoms, I am normal and functional again.
  • I recommend that experimenters get these supplements from Pipingrock
    – NAC: http://www.pipingrock.com/n-acetyl-cysteine
    – Preg: http://www.pipingrock.com/pregnenolone
2 Likes

I heard reports about this too and decided to try aspirin, believe it or not I had never taken aspirin in my life so I had no idea what the effect would be. It had a very dramatic effect but not a positive one, I felt terrible mentally and just let it wear off, I was back to normal by the end of the day. Such a harmless and commonly used drug shouldn’t produce the effect that it did so there is definently something going on in there.

That could be a temporary initial reaction, maybe if you try it longer the inflammation will subside and symptoms will improve. Maybe you are simply not comfortable having increased functioning or there is some sort of thing the inflammation is actually doing to support the brain and when the inflammation subsides, the thing, maybe pathogen, takes advantage of the reduced swelling, because swelling is usually an immune defensive response.
Interesting, maybe you can try NAC the other anti-inflammatory and if you get the same result, get tested for infection of the brain.

I did some research into NAC over a year ago when my son’s pdoc recommended it. I can’t get my son to take it but I now take it. I was surprised at the health benefits it can provide for everyone.

Just out of curiosity, like what? Did you try it? Your statement is a little ambiguous.

http://www.lef.org/magazine/2010/5/N-Acetyl-Cysteine/Page-01

http://www.webmd.com/vitamins-supplements/ingredientmono-1018-n-acetyl%20cysteine.aspx?activeingredientid=1018&activeingredientname=n-acetyl%20cysteine

http://wholehealthchicago.com/3400/nac-n-acetylcysteine/

And yes I have been taking it for over a year now as part of a healthy diet life style.