Alphagenomix Site for Medications

I hope my logic is correct in that if your current meds are working you can simply pick which category they are in and later take those other meds.

For instance: Risperidone works for me, so I would take the meds in the CYP2D6 category.

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I don’t think it’s that simple. No I really don’t think it’s that simple.

CYP1A2 fast metabolizer

CYP2C19
Slower metaboliser for some drugs

CYP2D610
CYP2D6
10 reduced metabolism

CYP3A5 non-expressor
This is common for Caucasians, but rare for African populations. As a CYP3A5 non-expressor you are unable to metabolize some common medications. This influences the synthesis of cholesterol, steroids and other lipids. The enzyme metabolizes drugs such as olanzapine, tacrolimus, nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.

From https://geneticoncept.com/index.html

Aripiprazole (Abilify)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Asenapine (Saphris)
[Preliminary Research. More than 750 people with the condition were studied, but the findings still need to be confirmed by the scientific community in an independent study of similar size.]

Sensitivity: LOW

Metabolism: HIGH

Chlorpromazine (Thorazine)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Clozapine (Clozaril)
Preliminary Research: Fewer than 750 people studied

Sensitivity: LOW

Metabolism: HIGH

Clozapine-induced weight gain
[Preliminary Research. More than 750 people with the condition were studied, but the findings still need to be confirmed by the scientific community in an independent study of similar size.]

LOW

Haloperidol (Haldol)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Iloperidone (Fanapt)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Lurasidone (Latuda)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Olanzapine (Zyprexa)
Preliminary Research: Fewer than 750 people studied

Sensitivity: LOW

Metabolism: HIGH

Perphenazine (Trilafon)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Promazine (Sparine)
Preliminary Research: Fewer than 750 people studied

Sensitivity: LOW

Metabolism: HIGH

Quetiapine (Seroquel)
[Preliminary Research. More than 750 people with the condition were studied, but the findings still need to be confirmed by the scientific community in an independent study of similar size.]

Sensitivity: HIGH

Metabolism: REDUCED

Risperidone (Risperdal)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Thioridazine (Mellaril)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Ziprasidone (Geodon)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Amitriptyline (Elavil)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Bupropion
Preliminary Research: Fewer than 750 people studied

Sensitivity: TYPICAL

Metabolism: NORMAL

Citalopram (Celexa)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Clomipramine (Anafranil)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Desipramine (Norpramin)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Doxepin (Sinequan, Silenor, Prudoxin, Zonalon)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Escitalopram (Lexapro)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Fluoxetine (Prozac)
[Preliminary Research. More than 750 people with the condition were studied, but the findings still need to be confirmed by the scientific community in an independent study of similar size.]

Sensitivity: LOW

Metabolism: REDUCED

Imipramine (Tofranil)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Nefazodone (Serzone)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Nortriptyline (Aventyl,Pamelor)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Paroxetine (Paxil)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Sertraline (Zoloft)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Trazodone (Oleptro)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Venlafaxine (Effexor)
Preliminary Research: Fewer than 750 people studied

Sensitivity: HIGH

Metabolism: REDUCED

Alprazolam (Xanax)
Preliminary Research: Fewer than 750 people studied

Sensitivity: NORMAL TO LOW

Metabolism: NORMAL TO HIGH

Buspirone (BuSpar)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Diazepam (Valium)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Midazolam (Versed)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

Phenobarbital triazolam (Halcion)
Preliminary Research: Fewer than 750 people studied

Sensitivity: NORMAL TO LOW

Metabolism: NORMAL TO HIGH

Zolpidem (Ambien)
Preliminary Research: Fewer than 750 people studied

Sensitivity: AVERAGE

Metabolism: INTERMEDIATE

I don’t get it o.O

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Those are @firemonkey’s results from genetic testing. It looked at which gene variants he had governing metabolizing medications and told him how he could expect all those medications to affect him if he took them.

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They are based on my genotypes which come from my 23andMe raw data.

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Ohhh ok I see. I’m actually waiting to get my raw genetic data back from sequencing as well. Should get here in a few months, then I have to get it interpreted…but hopefully I’ll know that info for myself soon as well :slight_smile: Personalized medicine is neat.

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Ok, you got me. I’m cheap.

I will have to get the testing done, but once I’m in school it will be tough to get around to it. I’m preparing to go to school (and because it has lazy advisers, I won’t be able to get in without a fight.)

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